
The Pill is Here: Resistance is NOT Futile (Yet)
Alright people listen up! It's Sarah Connor and I'm here to tell you about the latest threat disguised as a miracle cure. Eli Lilly the same guys who brought you... well never mind they're working on a daily obesity pill called orforglipron. They claim it'll help folks with Type 2 diabetes lose weight and manage their blood sugar with safety comparable to those needle based injections everyone's jabbing themselves with. This is how it starts people. First it's weight loss then it's… who knows? Maybe the machines will want to be thin too.
No Needles? Sounds Too Good to Be True
This orforglipron pill is supposed to be a "needle free alternative" in the weight loss and diabetes market. They're saying it's easier to manufacture more convenient and could give Eli Lilly a leg up on Novo Nordisk (the Ozempic people!) and other rivals. But don't be fooled by the convenience! Remember what Dyson said in the first Terminator? "The Skynet Funding Bill is passed. The system goes on line August 4th. Human decisions are removed from strategic defense." Convenience always comes at a price people! Always! This could be Skynet in a pill!
The Numbers Game: Wall Street vs. Reality
So the weight loss data and side effect rates were apparently in line with what those Wall Street types expected. But it fell short on some diabetes metrics. Eli Lilly's stock jumped 11% anyway. Typical. They tout that the highest dose helped patients lose about 7.9% of their weight (around 16 pounds) in 40 weeks. No plateau they say. Meaning... more weight loss! I've seen enough end of the world scenarios to know that exponential growth is NEVER a good thing! Never!
Side Effects: Because Nothing is Ever Free
Of course there's a catch. Side effects! About 8% of patients taking the highest dose quit due to side effects. Mostly gastrointestinal stuff – nausea vomiting diarrhea. Lovely. Vomiting affected 14% of those on the highest dose nausea hit 16% and diarrhea... well let's just say 26% had a blast. "I'll be back"... probably to the bathroom. The analysts at TD Cowen expected a 9% discontinuation rate. Someone's getting fired.
Blood Sugar Blues: Not Quite Ozempic
The pill helped lower hemoglobin A1c (blood sugar levels) by 1.3% to 1.6% from a starting level of 8%. The placebo group saw only a 0.1% reduction. Some analysts wanted a reduction of 1.8% to 2.1% like Ozempic delivers. Eli Lilly's CEO David Ricks is "pleased." Of course he is. But I'm not. We need better than "pleased" when our lives are on the line. This is a gut hormone mimicking drug and there are 7 late stage studies going on but what about the stage after that? Judgment Day stage!?
2026: Judgment Day for Diabetes (Maybe)
Eli Lilly plans to file for regulatory approval for obesity by the end of the year and for diabetes in 2026. 2026! Mark my words something big is gonna happen in 2026! If approved orforglipron could supposedly help more people access treatment. They're claiming this pill could be readily manufactured and launched at scale for use by people around the world. Sounds like global domination to me. It could help Eli Lilly solidify its dominance analysts are drooling at the thought of $150 billion by 2030! So remember always be vigilant. The future is not set. There is no fate but what we make for ourselves. And maybe just maybe lay off the sugar.
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